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Decoding Photoperiodic Time and Melatonin in Mammals: What Can We Learn from the Pars Tuberalis?

Aberdeen Centre for Energy Regulation and Obesity (ACERO), University of Aberdeen, 581 King ST, Aberdeen AB24 5UA, Scotland, UKd.hazlerigg{at}abdn.ac.uk

P. J. Morgan

Molecular Neuroendocrinology Group, The Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, Scotland, UK

S. Messager

Aberdeen Centre for Energy Regulation and Obesity (ACERO), University of Aberdeen, 581 King ST, Aberdeen AB24 5UA, Scotland, UK

The cellular and molecular mechanisms through which the melatonin signal is decoded to drive/synchronize photoperiodic responses remain unclear. Much of our current understanding of the processes involved in this readout derives from studies of melatonin action in the pars tuberalis of the anterior pituitary. Here, the authors review current knowledge and highlight critical gaps in our present understanding.

Key Words: Melatonin • photoperiod • pars tuberalis seasonality • prolactin

Journal of Biological Rhythms, Vol. 16, No. 4, 326-335 (2001)
DOI: 10.1177/074873001129002042


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