|
Sign In to gain access to subscriptions and/or personal tools.
|
Differential Control of Morning and Evening Components in the Activity Rhythm of Drosophila melanogaster—Sex-Specific Differences Suggest a Different Quality of Activity
Charlotte Helfrich-Förster
Zoologisches Institut, Auf der Morgenstelle 28, 72076 Tübingen
The rhythms of locomotor activity of male and virgin or mated female flies were compared in the Drosophila melanogaster wild-type strains Canton S, Berlin, and OregonR. Under light-dark conditions, most flies showed a bimodal activity pattern with a morning peak around lights-on and an evening peak before lights-off. For all strains, a distinct sexual dimorphism was observed in the phase of the morning peak. Males had a significantly earlier morning peak than females and consequently a larger phase angle between morning and evening peak ([.Psi]m, e). Under constant dark conditions, the morning component merged with the evening component to a unimodal activity band in about half of the flies. In those flies who maintained bimodality, the sex-specific difference in [.Psi]m, e disappeared. Other sex-specific differences were now apparent: Males showed a shorter free running period than females, and in two of the three strains, females were more active than males. Morning and evening components seem to contribute to the free-running period. Spontaneous or externally provoked change in [.Psi]m, e were correlated with period changes. In some flies, the morning and the evening components showed splitting, indicating that they are the output of two different oscillators. The sexual dimorphism in the phase of the morning peak under LDconditions suggests that the function of activity during morning and evening peak might be different, for example, during the morning peak, males are active to find females. Overall, the results underline the multioscillatory nature of Drosophila's circadian system.
Key Words: circadian rhythm • dual-oscillator model • entrainment • insects • sexual dimorphism
Journal of Biological Rhythms, Vol. 15, No. 2,
135-154 (2000)
DOI: 10.1177/074873040001500208
 CiteULike  Complore  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter What's this?
This article has been cited by other articles:
|
|
|
|
 
C. Helfrich-Forster
Does the Morning and Evening Oscillator Model Fit Better for Flies or Mice?
J Biol Rhythms,
August 1, 2009;
24(4):
259 - 270.
[Abstract]
[PDF]
|
|
|
|
|
|
|
D. Rieger, C. Wulbeck, F. Rouyer, and C. Helfrich-Forster
Period Gene Expression in Four Neurons Is Sufficient for Rhythmic Activity of Drosophila melanogaster under Dim Light Conditions
J Biol Rhythms,
August 1, 2009;
24(4):
271 - 282.
[Abstract]
[PDF]
|
|
|
|
|
|
|
A. Satoh, E. Yoshioka, and H. Numata
Circatidal activity rhythm in the mangrove cricket Apteronemobius asahinai
Biol Lett,
June 23, 2008;
4(3):
233 - 236.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Rieger, C. Fraunholz, J. Popp, D. Bichler, R. Dittmann, and C. Helfrich-Forster
The Fruit Fly Drosophila melanogaster Favors Dim Light and Times Its Activity Peaks to Early Dawn and Late Dusk
J Biol Rhythms,
October 1, 2007;
22(5):
387 - 399.
[Abstract]
[PDF]
|
|
|
|
|
|
|
E. Dolezelova, D. Dolezel, and J. C. Hall
Rhythm Defects Caused by Newly Engineered Null Mutations in Drosophila's cryptochrome Gene
Genetics,
September 1, 2007;
177(1):
329 - 345.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
W. Bachleitner, L. Kempinger, C. Wulbeck, D. Rieger, and C. Helfrich-Forster
Moonlight shifts the endogenous clock of Drosophila melanogaster
PNAS,
February 27, 2007;
104(9):
3538 - 3543.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Koh, J. M. Evans, J. C. Hendricks, and A. Sehgal
From the Cover: A Drosophila model for age-associated changes in sleep:wake cycles
PNAS,
September 12, 2006;
103(37):
13843 - 13847.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Lee, J. H. Bahn, and J. H. Park
Sex- and clock-controlled expression of the neuropeptide F gene in Drosophila
PNAS,
August 15, 2006;
103(33):
12580 - 12585.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Rieger, O. T. Shafer, K. Tomioka, and C. Helfrich-Forster
Functional Analysis of Circadian Pacemaker Neurons in Drosophila melanogaster
J. Neurosci.,
March 1, 2006;
26(9):
2531 - 2543.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Rieger, R. Stanewsky, and C. Helfrich-Forster
Cryptochrome, Compound Eyes, Hofbauer-Buchner Eyelets, and Ocelli Play Different Roles in the Entrainment and Masking Pathway of the Locomotor Activity Rhythm in the Fruit Fly Drosophila Melanogaster
J Biol Rhythms,
October 1, 2003;
18(5):
377 - 391.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. C. Hendricks
Genetic Models in Applied Physiology: Invited Review: Sleeping flies don't lie: the use of Drosophila melanogaster to study sleep and circadian rhythms
J Appl Physiol,
April 1, 2003;
94(4):
1660 - 1672.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. C. Hendricks, S. Lu, K. Kume, J. C.-P. Yin, Z. Yang, and A. Sehgal
Gender Dimorphism in the Role of cycle (BMAL1) in Rest, Rest Regulation, and Longevity in Drosophila melanogaster
J Biol Rhythms,
February 1, 2003;
18(1):
12 - 25.
[Abstract]
[PDF]
|
|
|
|
|
|
|
C. Helfrich-Forster, T. Edwards, K. Yasuyama, B. Wisotzki, S. Schneuwly, R. Stanewsky, I. A. Meinertzhagen, and A. Hofbauer
The Extraretinal Eyelet of Drosophila: Development, Ultrastructure, and Putative Circadian Function
J. Neurosci.,
November 1, 2002;
22(21):
9255 - 9266.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Tauber and B. P. Kyriacou
Insect Photoperiodism and Circadian Clocks: Models and Mechanisms
J Biol Rhythms,
August 1, 2001;
16(4):
381 - 390.
[Abstract]
[PDF]
|
|
|
|
|
