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Journal of Biological Rhythms
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Seasonal Variation of Blood Cholesterol Levels: Study Methodology

Philip A. Merriam

Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Department of Medicine, 55 Lake Avenue North, Worcester, MA 01655

Ira S. Ockene

Division of Cardiovascular Medicine, University of Massachusetts Medical School, Department of Medicine, 55 Lake Avenue North, Worcester, MA 01655

James R. Hebert

Milagros C. Rosal

Charles E. Matthews

Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Department of Medicine, 55 Lake Avenue North, Worcester, MA 01655

This manuscript provides a description of the methodology used in the Seasonal Variation of Blood Cholesterol Levels (SEASON) study, with the intent of informing the scientific community of the available data sets and to invite a dialogue with scientists in complementary fields. The primary aim of the SEASON study is to describe and delineate the causes of seasonal variation of blood lipid levels in the general population. This research project is designed specifically to systematically collect and analyze a number of important variables necessary to study the role of seasonality in blood lipids and relevant covariates.

Key Words: study methodology • seasonal variation • cholesterol • blood lipids

Journal of Biological Rhythms, Vol. 14, No. 4, 330-339 (1999)
DOI: 10.1177/074873099129000669


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